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Clinical Trial Design and Methodology

We examine methods and technological innovations to improve the design of clinical trials.

One important topic in clinical trial design is that of adaptive study protocols. Our research assesses how integrated adaptive study designs and protocols can improve early-phase clinical trials to increase efficiency and save costs.

We are also investigating how adaptations to standardised, template or algorithm-based approaches to managing adverse reactions can be applied to and improved for early-phase clinical trials.

Our clinical trial design and methodology research unit is led by Dr. Ulrike Lorch. She is currently investigating how computer-based automated learning could be used to develop an algorithm that provides grading for adverse drug reactions based on input factors such as symptoms, laboratory results and patient effects.

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richmond research institute

We have a track record in conducting clinical research.


We present our scientific findings at meetings.


Our academic research helps improve lives and strengthens scientific insights.