Publications - Richmond Research Institute

Confirmation of the cardiac safety of nolasiban in a randomised cohort of healthy female volunteers

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Comparing the consistency of electrocardiogram interval measurements by resting ECG versus 12-lead Holter

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A Phase 1 Study to Investigate the Effects of Cortexolone 17α-Propionate, Also Known as Clascoterone, on the QT Interval Using the Meal Effect to Demonstrate ECG Assay Sensitivity

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Effects of progesterone and estradiol on QT subintervals over the course of a menstrual cycle

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Do hERG blocking agents further increase the risk of sudden cardiac death in patients with type 1 diabetes?

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Comparison of the effects of levofloxacin on QT/QTc interval assessed in both healthy Japanese and Caucasian subjects (2011)

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Insulin at normal physiological levels does not prolong QTc interval in thorough QT studies performed in healthy volunteers (2012)

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Shortening of the QT Interval After Food Can Be Used to Demonstrate Assay Sensitivity in Thorough QT Studies (2012)

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Thorough QT study of the effect of oral moxifloxacin on QTc interval in the fed and fasted state in healthy Japanese and Caucasian subjects (2013)

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Estimation of the Power of the Food Effect on QTc to Show Assay Sensitivity (2017)

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Diurnal Profile of the QTc Interval Following Moxifloxacin Administration (2019)

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Effects of the Fluoroquinolones Moxifloxacin and Levofloxacin on the QT Subintervals: Sex Differences in Ventricular Repolarization (2019)

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The Cardiovascular Effects of a Meal: J-Tpeak and Tpeak-Tend Assessment and Further Insights Into the Physiological Effects (2019)

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Our Research & Publications

We have published over 250 scientific articles in peer-reviewed journals and regularly present our research at scientific meetings.

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Cardiac Publications

Confirmation of the cardiac safety of nolasiban in a randomised cohort of healthy female volunteers

Comparing the consistency of electrocardiogram interval measurements by resting ECG versus 12-lead Holter

A Phase 1 Study to Investigate the Effects of Cortexolone 17α-Propionate, Also Known as Clascoterone, on the QT Interval Using the Meal Effect to Demonstrate ECG Assay Sensitivity

Effects of progesterone and estradiol on QT subintervals over the course of a menstrual cycle

Do hERG blocking agents further increase the risk of sudden cardiac death in patients with type 1 diabetes?

Comparison of the effects of levofloxacin on QT/QTc interval assessed in both healthy Japanese and Caucasian subjects (2011)

Insulin at normal physiological levels does not prolong QTc interval in thorough QT studies performed in healthy volunteers (2012)

Shortening of the QT Interval After Food Can Be Used to Demonstrate Assay Sensitivity in Thorough QT Studies (2012)

Thorough QT study of the effect of oral moxifloxacin on QTc interval in the fed and fasted state in healthy Japanese and Caucasian subjects (2013)

Estimation of the Power of the Food Effect on QTc to Show Assay Sensitivity (2017)

Diurnal Profile of the QTc Interval Following Moxifloxacin Administration (2019)

Effects of the Fluoroquinolones Moxifloxacin and Levofloxacin on the QT Subintervals: Sex Differences in Ventricular Repolarization (2019)

The Cardiovascular Effects of a Meal: J-Tpeak and Tpeak-Tend Assessment and Further Insights Into the Physiological Effects (2019)

Ethnicity Publications

Investigating the Effect of Intravenous APD421 (Amisulpride) and the Ethnic Differences Between Japanese and Caucasians on Cardiac Conduction

J. Täubel 1, G. Ferber 2, G. Fox , S. 3 Ferna. ndes , U. Lorch , A John Camm 1 1 4

Cardiac Safety of Rupatadine in a Single-Ascending-Dose and Multiple-Ascending-Dose Study in Healthy Japanese Subjects

J. Taubel ¨ 1,2, G. Ferber3, S. Fernandes1, E. Santamar´ıa4, and I. Izquierdo4

Diurnal and Racial Variance of White Blood Cell Parameters in Early Phase Clinical Trials

S. Coates 1; S Fernandes 1, D Wang 2, C Umukoro 1, D Djumanov 1, U Lorch 1, J Tiiubel 1,3

Liver Publications

The influence of a low fat diet and hospitalisation on liver function tests in healthy Japanese and Caucasian male volunteers (2013)

U Lorch , J Singh , D Djumanov , J Täubel

Trial Methodology Publications

Practical risk management in early phase clinical trials

Simon Coates1 & Jörg Täubel1,2 & Ulrike Lorch1

A Box-Cox Approach to QT Interval Correction for Heart Rate

Duolao Wang, PhD 1* , Radivoj Arezina, MD 2 , Jorg Taubel, MD 2

Three steps to writing adaptive study protocols in the early phase clinical development of new medicines

Ulrike Lorch 1*, Martin O’Kane 2 and Jorg Taubel 1

The practical application of adaptive study design in early phase clinical trials: a retrospective analysis of time savings

U. Lorch & K. Berelowitz & C. Ozen & A. Naseem & E. Akuffo & J. Taubel

Mason-Likar electrode configuration can confound the recognition of electrode cable interchange

Velislav N. Batchvarov, MD, PhD A. John Camm, MD, FACC, FAHA, Dilshat Djumanov, PhD Jorg Taubel, FFPM, MD

Comparison Of Ecg Parameters Using Ge Getemed Continuous Ecg Holter And Mac-1200 Bedside Ecg

Jörg Täubel 1,2, Teresa Del Bianco 1 , Sara Fernandes 1 , Boaz Mendzelevski 3 , Dilshat Djumanov 1 , George Ferber 4

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Richmond Research Institute
St George's Hospital
University of London
Cranmer Terrace
Tooting, London
SW17 0RE

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