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Dr Ulrike Lorch

Group Scientific Lead – Clinical Trial Design and Methodology

Cardiac Health

Dr Ulrike Lorch is a highly experienced research physician having conducted more than 220 early phase clinical trials as Principal Investigator or Co-investigator. She has special expertise in adaptive study design in early phase clinical trials, First-into-Human and other exploratory studies in healthy volunteers and patients of all ages, ethnic comparison, cardiac safety (including TQT), pain and gastrointestinal pH monitoring studies.

She holds Specialist Accreditation in Pharmaceutical Medicine and is a Fellow of the Faculty of Pharmaceutical Medicine of the Royal Colleges of Physicians (UK) and a Fellow of the Royal College of Anaesthetists (UK). Dr Lorch is Educational Supervisor for physicians participating in Pharmaceutical Medicine Specialist Training. She is a member of the Education Committee and a member of the Board of Examiners of the Faculty of Pharmaceutical Medicine.

In her role as Medical Director at Richmond Pharmacology she was instrumental in obtaining Standard and Supplementary Medicines and Healthcare Products Regulatory Agency (MHRA) Phase I Accreditation. As a Principal Investigator she is accredited to conduct all types of Phase I studies, including those that, due to potential risks, require review by the Expert Advisory Group in addition to the standard review by the MHRA.

Dr Lorch is a member of the British Association of Pharmaceutical Physicians (BrAPP), a Committee member of the Association for Human Pharmacology in the Pharmaceutical Industry (AHPPI, UK), the Phase I Advisory Group (National Research Ethics Service, Health Research Authority, UK), the Japanese Society of Pharmacology and Therapeutics and the Arbeitsgemeinschaft fur Angewandte Humanpharmakologie (AGAH, Germany). She is also a member of the Trial Steering Group Of the AGILE (Coronavirus Drug Testing Initiative) Seamless Phase I/IIa Platform.

At Richmond Research Institute Dr Lorch leads our clinical trial design and methodology research group. She is currently investigating how computer-based automated learning could be used to develop an algorithm that provides grading for adverse drug reactions based on input factors such as symptoms, laboratory results and patient effects.

Fellowships

  • Fellow: Faculty of Pharmaceutical Medicine of the Royal Colleges of Physicians
  • Fellow: Royal College of Anaesthetists

Memberships

  • Member: Board of Examiners of the Faculty of Pharmaceutical Medicine
  • Member: British Association of Pharmaceutical Physicians
  • ‍Member: Association for Human Pharmacology in the Pharmaceutical Industry
  • Member: Phase I Advisory Group
  • Member: Japanese Society of Pharmacology and Therapeutics
  • Member: Arbeitsgemeinschaft fur Angewandte Humanpharmakologie (Germany)
  • Member: Trial Steering Group Of the AGILE
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